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Dermex 0.05 % ointment

Dermex

COMPOSITION:
Dermex? 0.05 % cream: Each 10 gm Dermex cream contations Clobetasol propionate BP 5 gm. Dermex? 0.05 % ointment: Each 10 gm Dermex ointment contains Clobetasol propionate BP 5gm.

Manufacturer : Opsonin Pharma Ltd.

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Dermex

COMPOSITION:
Dermex? 0.05 % cream: Each 10 gm Dermex cream contations Clobetasol propionate BP 5 gm. Dermex? 0.05 % ointment: Each 10 gm Dermex ointment contains Clobetasol propionate BP 5gm.

INDICATIONS:
Dermex is indicated in:
1. Initial control of all forms of hyperacute eczema in all age groups
(in children for no longer then a few days).
2. Chronic hyperkeratotic eczema of the hands and feet and patches of chronic lichen simplex
3. Chronic hyperkeratotic psoriasis of any area of the body
4. Severe acute photosensitivity
5. Hypertrophic lichen planus
6. Localized bullous disorders
7. Keloid scarring
8. Pretibial myxoedema
9. Vitiligo
10. Suppression of reaction after cryotherapy

DOSAGE AND ADMINISTRATION:
Apply sparingly to the affected area once or twice daily until improvement occurs. As with other highly active topical steroid preparations, therapy should be discontinued when control is achieved. If a longer course is necessary, it is recommended that treatment should not be continued for more than four weeks without the patient's condition being observed. Repeated short courses of Dermex may be used to control exacerbations. If continuous steroid treatment is necessary, a less potent preparation should be used. In very resistant lesions, especially where there is hyperkeratosis, the anti-inflammatory effect of Dermex can be enhanced, if necessary, by occluding the treatment area with polythene film. Only overnight occlusion is usually adequate to bring about a satisfactory response. Thereafter, improvement can usually be maintained by application without occlusion.

SIDE EFFECTS:
Provided the weekly dosage is less than 50g in adults, any pituitary-adrenal suppression is likely to be transient with a rapid return to normal values once the short course of steroid therapy has ceased. The same applies to children given proportionate dosage. Use of occlusive dressings increases the absorption of topical corticosteroids. Prolonged and intensive treatment with a highly active corticosteroid preparation may cause atrophic changes, such as thinning, striae and dilatation of the superficial blood vessels, particularly when occlusive dressings are used or where skin folds are involved.

USE IN PREGNANCY AND LACTATION:
Clobetasol propionate should be avoided in pregnant women. Mothers using large amounts of the drug should be aware of potential excretion in milk.

CONTRAINDICATION AND PRECAUTION:
Clobetasol propionate is contraindicated in:
1. Cutaneous infections such as impetigo, tinea corporis and herpes simplex
2. Infestations such as scabies
3. Neonates (Children less than one year old)
4. Acne vulgaris
5. Rosacea
6. Gravitational ulceration
Long term continuous therapy with Clobetasol propionate should be avoided, particularly in infants and children, in whom adrenal suppression occurs readily. If Clobetasol propionate is required for use in children, it is recommended that the treatment should be reviewed on weekly basis. It should be noted that the infants napkin may act as occlusive dressing. The face more than other area of the body, may exhibit atrophic changes after prolonged treatment with potent topical corticosteroids. This must be borne in mind when treating facial conditions which warrants use of Clobetasol propionate and frequent observation of the patients is important.

Presentations:
Dermex 0.05 % cream : Tube containing 10 gm cream.
Dermex 0.05 % ointment : Tube containing 10 gm ointment.

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Dermex 0.05 % ointment

Dermex 0.05 % ointment

Dermex

COMPOSITION:
Dermex? 0.05 % cream: Each 10 gm Dermex cream contations Clobetasol propionate BP 5 gm. Dermex? 0.05 % ointment: Each 10 gm Dermex ointment contains Clobetasol propionate BP 5gm.

Manufacturer : Opsonin Pharma Ltd.

Write your review